Characterization of pellino1 and pellino2 in toll-like receptor signaling

Pellino family proteins were first identified as interacting partners with kinase IRAK1 in TLR/IL-1R pathway. There are three Pellino isoforms in human cells, termed Pellino1, Pellino2 and Pellino3. They contain a FHA and a RING domain in the N- and C-terminus regions respectively. The major varianc...

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Bibliographic Details
Main Author: Dai, Liang
Other Authors: -
Format: Theses and Dissertations
Language:English
Published: Nanyang Technological University 2012
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Online Access:http://hdl.handle.net/10356/50864
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Institution: Nanyang Technological University
Language: English