Analysing the depletion of microglia and myeloid cells in the cd11b-dtr/cd45-dtr mice.

• Main Author: Tan, Kah Sheng.
• Other Authors: Klaus Erik Karjalainen
• Format: Final Year Project
• Language: English
• Published: 2013
• Subjects: DRNTU::Science::Biological sciences::Microbiology::Immunology
• Online Access: http://hdl.handle.net/10356/52456
• Institution: Nanyang Technological University

Predecessor experiments have shown that microglia and myeloid cells are depleted in cd45-dtr homozygous mice but we wanted to test if cd11b-dtr/cd45-dtr heterozygous mice are able to deplete these cells just as efficiently. We generated transgenic cd11b-dtr/cd45-dtr heterozygous mice and administere...