The identification of cis-regulatory elements of runx3

• Main Author: Nah, Giselle Sek Suan
• Other Authors: School of Biological Sciences
• Format: Theses and Dissertations
• Language: English
• Published: 2013
• Subjects: DRNTU::Science::Biological sciences
• Online Access: http://hdl.handle.net/10356/53732
• Institution: Nanyang Technological University

The RUNX3 gene is essential for the development of multiple cell lineages and is frequently involved in a variety of cancers and immunological diseases. Despite such frequent association with human diseases, the transcriptional regulation of Runx3 remains elusive. Owing to the huge ~350 kb Runx3 loc...