Synthesis and biological studies of benzofuran-based estrogen receptor α modulators, pyridone alkaloids and zanamivir
In the first chapter, the search for new estrogen receptor alpha (ERα) modulators commenced with a trial molecular screening and 5,6-dihydroxybenzofuran was identified as a possible drug target for ERα. The target molecular modelling compound and a series of 5,6-dihydroxybenzofurans were synthesized...
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| 格式: | Theses and Dissertations |
| 語言: | English |
| 出版: |
2014
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| 在線閱讀: | http://hdl.handle.net/10356/55776 |
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| 機構: | Nanyang Technological University |
| 語言: | English |