Synthesis and biological studies of benzofuran-based estrogen receptor α modulators, pyridone alkaloids and zanamivir

In the first chapter, the search for new estrogen receptor alpha (ERα) modulators commenced with a trial molecular screening and 5,6-dihydroxybenzofuran was identified as a possible drug target for ERα. The target molecular modelling compound and a series of 5,6-dihydroxybenzofurans were synthesized...

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Bibliographic Details
Main Author: Leow, Min Li
Other Authors: Liu Xuewei
Format: Theses and Dissertations
Language:English
Published: 2014
Subjects:
Online Access:http://hdl.handle.net/10356/55776
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Institution: Nanyang Technological University
Language: English