Molecular mechanics of asialogycoprotetin receptor interactions with ligands

Human asialoglycoprotein receptor (ASGPR) is also known as hepatic lectin integral membrane protein, which is responsible for the clearance of desialyl galactose-terminal glycoproteins from the circulation by receptor-mediated endocytosis. Studies have shown that the main interaction of hepatocytes...

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Main Author: Chew, Lay Leng.
Other Authors: Liao, Kin
Format: Theses and Dissertations
Published: 2008
Subjects:
Online Access:http://hdl.handle.net/10356/5601
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Institution: Nanyang Technological University
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spelling sg-ntu-dr.10356-56012023-03-11T17:06:03Z Molecular mechanics of asialogycoprotetin receptor interactions with ligands Chew, Lay Leng. Liao, Kin School of Mechanical and Aerospace Engineering DRNTU::Engineering::Bioengineering Human asialoglycoprotein receptor (ASGPR) is also known as hepatic lectin integral membrane protein, which is responsible for the clearance of desialyl galactose-terminal glycoproteins from the circulation by receptor-mediated endocytosis. Studies have shown that the main interaction of hepatocytes with engineered scaffold is the recognition between this receptor and galactose ligands. Using the HyperChem Computational Chemistry program, the energy between the ASGPR and the galactose ligand is obtained. Master of Science (Biomedical Engineering) 2008-09-17T10:54:41Z 2008-09-17T10:54:41Z 2005 2005 Thesis http://hdl.handle.net/10356/5601 Nanyang Technological University application/pdf
institution Nanyang Technological University
building NTU Library
continent Asia
country Singapore
Singapore
content_provider NTU Library
collection DR-NTU
topic DRNTU::Engineering::Bioengineering
spellingShingle DRNTU::Engineering::Bioengineering
Chew, Lay Leng.
Molecular mechanics of asialogycoprotetin receptor interactions with ligands
description Human asialoglycoprotein receptor (ASGPR) is also known as hepatic lectin integral membrane protein, which is responsible for the clearance of desialyl galactose-terminal glycoproteins from the circulation by receptor-mediated endocytosis. Studies have shown that the main interaction of hepatocytes with engineered scaffold is the recognition between this receptor and galactose ligands. Using the HyperChem Computational Chemistry program, the energy between the ASGPR and the galactose ligand is obtained.
author2 Liao, Kin
author_facet Liao, Kin
Chew, Lay Leng.
format Theses and Dissertations
author Chew, Lay Leng.
author_sort Chew, Lay Leng.
title Molecular mechanics of asialogycoprotetin receptor interactions with ligands
title_short Molecular mechanics of asialogycoprotetin receptor interactions with ligands
title_full Molecular mechanics of asialogycoprotetin receptor interactions with ligands
title_fullStr Molecular mechanics of asialogycoprotetin receptor interactions with ligands
title_full_unstemmed Molecular mechanics of asialogycoprotetin receptor interactions with ligands
title_sort molecular mechanics of asialogycoprotetin receptor interactions with ligands
publishDate 2008
url http://hdl.handle.net/10356/5601
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