Molecular mechanics of asialogycoprotetin receptor interactions with ligands

• Main Author: Chew, Lay Leng.
• Other Authors: Liao, Kin
• Format: Theses and Dissertations
• Published: 2008
• Subjects: DRNTU::Engineering::Bioengineering
• Online Access: http://hdl.handle.net/10356/5601
• Institution: Nanyang Technological University

Human asialoglycoprotein receptor (ASGPR) is also known as hepatic lectin integral membrane protein, which is responsible for the clearance of desialyl galactose-terminal glycoproteins from the circulation by receptor-mediated endocytosis. Studies have shown that the main interaction of hepatocytes...