Analysis of DNA damage response in mouse embryonic stem cells

Embryonic stem cells have the intrinsic capacity to proliferate indefinitely and this renders them highly susceptible to DNA damage in the form of double strand breaks (DSBs). DSBs are recognized as the most lethal DNA damage lesion and this put ESCs in a vulnerable position. It was reported that t...

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Bibliographic Details
Main Author: Xu, Ruiping
Other Authors: Li Hoi Yeung
Format: Theses and Dissertations
Language:English
Published: 2015
Subjects:
Online Access:http://hdl.handle.net/10356/62058
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Institution: Nanyang Technological University
Language: English