Regulation of differentiation by rhogtpases in mouse embryonic stem cells

RhoGTPases plays an essential role in the regulation of actin cytoskeleton that is important for many cellular activities in most mammalian cell types. Here, we report that RhoA, a RhoGTPase, preferentially directs cell fate specification towards endoderm and mesoderm lineages, while inhibiting ecto...

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Bibliographic Details
Main Author: Tan, Mei Hua
Other Authors: Koh Cheng Gee
Format: Theses and Dissertations
Language:English
Published: 2015
Subjects:
Online Access:https://hdl.handle.net/10356/65033
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Institution: Nanyang Technological University
Language: English