Analysis of DNA damage response in mouse embryonic stem cells

• المؤلف الرئيسي: Xu, Ruiping
• مؤلفون آخرون: Li Hoi Yeung
• التنسيق: Theses and Dissertations
• اللغة: English
• منشور في: 2015
• الموضوعات: DRNTU::Science::Biological sciences::Molecular biology
• الوصول للمادة أونلاين: http://hdl.handle.net/10356/62058

Embryonic stem cells have the intrinsic capacity to proliferate indefinitely and this renders them highly susceptible to DNA damage in the form of double strand breaks (DSBs). DSBs are recognized as the most lethal DNA damage lesion and this put ESCs in a vulnerable position. It was reported that t...