Elucidating the role of SCD1 in B cell development and function

• Main Author: Loo, Larry Sai Weng
• Other Authors: Lam Kong Peng
• Format: Theses and Dissertations
• Language: English
• Published: 2015
• Subjects: DRNTU::Science::Biological sciences::Molecular biology
• Online Access: http://hdl.handle.net/10356/63295
• Institution: Nanyang Technological University

Stearoyl-coenzyme A (CoA) desaturase (SCD) enzymes are a family of δ-9 fatty acid desaturases that catalyse the de novo synthesis of monounsaturated fatty acids (MUFAs) from endogenous or dietary saturated fatty acids (SFAs). Here, we reported the loss of SCD1 leads to the down-regulation of B1 cell...