The biosynthesis of vitamin E in the bacteria Escherichia coli
The lipid antioxidant vitamin E is among the supplements essential for humans and animals. Its biosynthesis pathways in plants and cyanobacteria have been elucidated and studied, cloned and expressed in order to enhance the vitamin E contents of producer crops. For decades, Escherichia coli has b...
Saved in:
| Main Author: | |
|---|---|
| Other Authors: | |
| Format: | Theses and Dissertations |
| Language: | English |
| Published: |
2015
|
| Subjects: | |
| Online Access: | http://hdl.handle.net/10356/64419 |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
| Institution: | Nanyang Technological University |
| Language: | English |
| id |
sg-ntu-dr.10356-64419 |
|---|---|
| record_format |
dspace |
| spelling |
sg-ntu-dr.10356-644192023-03-03T15:59:54Z The biosynthesis of vitamin E in the bacteria Escherichia coli Lieviant, Jane Andrea Song Hao School of Chemical and Biomedical Engineering DRNTU::Engineering::Bioengineering The lipid antioxidant vitamin E is among the supplements essential for humans and animals. Its biosynthesis pathways in plants and cyanobacteria have been elucidated and studied, cloned and expressed in order to enhance the vitamin E contents of producer crops. For decades, Escherichia coli has been the primary workhorse for recombinant pharmaceuticals, especially for small molecules and proteins not requiring complex posttranslational modifications. This work reviews the biosynthesis of tocochromanols, their functions, and past efforts in engineering the pathway, and the possibilities for E. coli as the optimal host system. Master of Science (Biomedical Engineering) 2015-05-26T07:32:53Z 2015-05-26T07:32:53Z 2014 2014 Thesis http://hdl.handle.net/10356/64419 en 40 p. application/pdf |
| institution |
Nanyang Technological University |
| building |
NTU Library |
| continent |
Asia |
| country |
Singapore Singapore |
| content_provider |
NTU Library |
| collection |
DR-NTU |
| language |
English |
| topic |
DRNTU::Engineering::Bioengineering |
| spellingShingle |
DRNTU::Engineering::Bioengineering Lieviant, Jane Andrea The biosynthesis of vitamin E in the bacteria Escherichia coli |
| description |
The lipid antioxidant vitamin E is among the supplements essential for humans and
animals. Its biosynthesis pathways in plants and cyanobacteria have been elucidated and
studied, cloned and expressed in order to enhance the vitamin E contents of producer
crops. For decades, Escherichia coli has been the primary workhorse for recombinant
pharmaceuticals, especially for small molecules and proteins not requiring complex posttranslational
modifications. This work reviews the biosynthesis of tocochromanols, their
functions, and past efforts in engineering the pathway, and the possibilities for E. coli as
the optimal host system. |
| author2 |
Song Hao |
| author_facet |
Song Hao Lieviant, Jane Andrea |
| format |
Theses and Dissertations |
| author |
Lieviant, Jane Andrea |
| author_sort |
Lieviant, Jane Andrea |
| title |
The biosynthesis of vitamin E in the bacteria Escherichia coli |
| title_short |
The biosynthesis of vitamin E in the bacteria Escherichia coli |
| title_full |
The biosynthesis of vitamin E in the bacteria Escherichia coli |
| title_fullStr |
The biosynthesis of vitamin E in the bacteria Escherichia coli |
| title_full_unstemmed |
The biosynthesis of vitamin E in the bacteria Escherichia coli |
| title_sort |
biosynthesis of vitamin e in the bacteria escherichia coli |
| publishDate |
2015 |
| url |
http://hdl.handle.net/10356/64419 |
| _version_ |
1759854426825162752 |