Understanding the effects of cofactor Ufd1 and Actin binding to p97

• Main Author: Sim, Benjamin Kunyi
• Other Authors: Li Hoi Yeung
• Format: Final Year Project
• Language: English
• Published: 2016
• Subjects: DRNTU::Science
• Online Access: http://hdl.handle.net/10356/67352
• Institution: Nanyang Technological University

p97/Valosin-containing protein (VCP) is a member of the AAA-ATPase family and it is involved in a diverse range of cellular activities such as protein degradation and membrane reformation pathways. The highly conserved ATPase functions as a homohexamer and the key to its multifunctionality lies with...