ATP binding to p97/VCP D1 domain regulates selective recruitment of adaptors to its proximal N-domain

p97/Valosin-containing protein (VCP) is a member of the AAA-ATPase family involved in many cellular processes including cell division, intracellular trafficking and extraction of misfolded proteins in endoplasmic reticulum-associated degradation (ERAD). It is a homohexamer with each subunit containi...

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Bibliographic Details
Main Authors: Chia, Wei Sheng, Chia, Diana Xueqi, Rao, Feng, Nun, Shoshana Bar, Shochat, Susana Geifman
Other Authors: School of Biological Sciences
Format: Article
Language:English
Published: 2013
Subjects:
Online Access:https://hdl.handle.net/10356/99093
http://hdl.handle.net/10220/10921
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Institution: Nanyang Technological University
Language: English