Structural and molecular characterization of human FK506-binding protein 25 (FKBP25), a nuclear immunophilin

• Main Author: Prakash, Ajit
• Other Authors: Yoon Ho Sup
• Format: Theses and Dissertations
• Language: English
• Published: 2016
• Subjects: DRNTU::Science::Biological sciences
• Online Access: https://hdl.handle.net/10356/68904
• Institution: Nanyang Technological University

Human FK506 binding protein (FKBP25), a 25 kDa nuclear protein, is a member of the FK506-binding protein family with peptidyl-prolyl cis-trans isomerase (PPIase) activity. It has a conserved C-terminal FK506 binding domain (FKBD), which binds with immunosuppressive drugs such as FK506 and rapamycin...