Electrospun fiber-mediated siRNA delivery and Gene silencing

• Main Author: Long, Hongyan
• Other Authors: Chew Sing Yian
• Format: Theses and Dissertations
• Language: English
• Published: 2016
• Subjects: DRNTU::Engineering
• Online Access: http://hdl.handle.net/10356/69020
• Institution: Nanyang Technological University

While substrate topography influences cell responses, RNA interference (RNAi) has also emerged as a potent method for understanding and directing cell fate. In particular, the three dimensional (3D) electrospun fibers can offer biomimicking topographical signal to alter cell phenotypes, while RNAi c...