Two ‘Detailed views’ on X chromosome inactivation

Xist (X-inactive specific transcript), a prototype long non-coding RNA, is essential for establishing X chromosome inactivation (XCI) in early embryos. However, its role in maintaining XCI in soma is unclear. When Xist was conditionally deleted in somatic cells from the inactive X (Xi∆Xist ), only r...

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Bibliographic Details
Main Author: Hong, Ru
Other Authors: Chen Xin
Format: Theses and Dissertations
Language:English
Published: 2016
Subjects:
Online Access:https://hdl.handle.net/10356/69087
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Institution: Nanyang Technological University
Language: English