Genome-wide RNAi screen identify melanoma-associated antigen Mageb3 involved in X chromosome inactivation

Genome-wide RNAi screen identify melanoma-associated antigen Mageb3 involved in X chromosome inactivation

Xist (inactivated X chromosome specific transcript) is a prototype long noncoding RNA in charge of epigenetic silencing of one X chromosome in each female cell in mammals. In a genetic screen, we identify Mageb3 and its homologs Mageb1 and Mageb2 as genes functionally required for Xist-mediated gene...

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Bibliographic Details
Main Authors: Li, Wei, Hong, Ru, Lai, Lan-Tian, Dong, Qiman, Ni, Peiling, Chelliah, Rosi, Huq, Mehnaz, Siti Nadirah Ismail, Chandola, Udita, Ang, Zhiwei, Lin, Bingqing, Chen, Xin, Chen, Lingyi, Zhang, Li-Feng
Other Authors: School of Biological Sciences
Format: Article
Language:English
Published: 2020
Subjects:
Science::Biological sciences
Xist
Mageb3
Online Access:https://hdl.handle.net/10356/139663
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Institution: Nanyang Technological University
Language: English

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https://hdl.handle.net/10356/139663

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