Biochemical and biophysical studies of the regulation of chromatin folding and self-association by the N-terminal histone tails

• Main Author: Chen, Qinming
• Other Authors: Lars Nordenskiold
• Format: Theses and Dissertations
• Language: English
• Published: 2016
• Subjects: DRNTU::Science
• Online Access: http://hdl.handle.net/10356/69215
• Institution: Nanyang Technological University

As the carrier of genomic DNA in eukaryotic cells, chromatin is one of the key factors involved in gene regulation. Many studies have revealed the general behavior of chromatin, whose basic feature is the assembly of nucleosome into array fibers. It has been identified that many factors, like cation...