Single-molecule force spectroscopy on histone H4 tail-cross-linked chromatin reveals fiber folding
The eukaryotic genome is highly compacted into a protein-DNA complex called chromatin. The cell controls access of transcriptional regulators to chromosomal DNA via several mechanisms that act on chromatin-associated proteins and provide a rich spectrum of epigenetic regulation. Elucidating the mech...
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Main Authors: | , , , , , |
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Other Authors: | |
Format: | Article |
Language: | English |
Published: |
2018
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Subjects: | |
Online Access: | https://hdl.handle.net/10356/87233 http://hdl.handle.net/10220/44349 |
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Institution: | Nanyang Technological University |
Language: | English |