Recognition of A-U and U-A base pairs in RNA duplexes by modified peptide nucleic acids

• المؤلف الرئيسي: Yuan, Zhen
• مؤلفون آخرون: Chen Gang
• التنسيق: Theses and Dissertations
• اللغة: English
• منشور في: 2017
• الموضوعات: DRNTU::Science::Biological sciences
• الوصول للمادة أونلاين: http://hdl.handle.net/10356/69812
• المؤسسة: Nanyang Technological University

RNA triplex structures play vital roles in regulating various biological processes, and have attracted a Jot of interest in designing TFOs (triplex-fonning oligomers) that could selectively and specifically bind to the nuclei acid duplex. The PNAs (peptide nucleic acids), with the natural nucleic ac...