Machine learning methods for predicting cancer drug effects from signaling and cell fate data

• Main Author: Mishra Shital Kumar
• Other Authors: Zheng Jie
• Format: Theses and Dissertations
• Language: English
• Published: 2017
• Subjects: DRNTU::Engineering::Computer science and engineering::Information systems::Models and principles
• Online Access: http://hdl.handle.net/10356/70489
• Institution: Nanyang Technological University

An important area of research within the discipline of the Computational Systems Biology is to investigate the mechanisms of determination of cell fate. As the cellular development progresses, a cell goes through several phenotypes (e.g. Apoptosis, Proliferation, G1, S, G2 and M). Apoptosis, which i...