Computational cell fate modelling for discovery of rewiring in apoptotic network for enhanced cancer drug sensitivity

The ongoing cancer research has shown that malignant tumour cells have highly disrupted signalling transduction pathways. In cancer cells, signalling pathways are altered to satisfy the demands of continuous proliferation and survival. The changes in signalling pathways supporting uncontrolled cell...

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Bibliographic Details
Main Authors: Chua, Huey Eng, Zhang, Fan, Zheng, Jie, Mishra, Shital Kumar, Bhowmick, Sourav Saha
Other Authors: School of Computer Engineering
Format: Article
Language:English
Published: 2015
Subjects:
Online Access:https://hdl.handle.net/10356/97165
http://hdl.handle.net/10220/25636
http://www.biomedcentral.com/qc/1752-0509/9/S1/S4
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Institution: Nanyang Technological University
Language: English