Establishment and characterisation of CRTC1 knockout in rodent hippocampal neurons
CRTC1 is a transcriptional modulator that is crucial for learning and memory. At present, a conditional knockout mouse has never been studied either in neuronal cultures or live animals. In this report, we propose the use of a single lentiviral vector to deliver Cas9 and guide RNAs (gRNAs) into neur...
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| 格式: | Final Year Project |
| 語言: | English |
| 出版: |
2017
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| 在線閱讀: | http://hdl.handle.net/10356/71555 |
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