Synthesis of curvulone B and allahabadolactone, and the development of a diastereoselective Tsuji-Trost cyclisation

• Main Author: Wang, Kongchen
• Other Authors: Roderick Wayland Bates
• Format: Theses and Dissertations
• Language: English
• Published: 2017
• Subjects: DRNTU::Science::Chemistry::Organic chemistry::Organic synthesis
• Online Access: http://hdl.handle.net/10356/73049
• Institution: Nanyang Technological University

The first chapter describes the synthesis of curvulone B featuring a strategy of cross metathesis and oxa-Michael addition in the construction of the desired cis-THP ring. This strategy is one of the most effective tools in the synthesis of THP rings containing natural products. o-Chlorobenzyl ether...