Mechanistic, enzymatic and structural insights into M. tuberculosis alkyl-hydroperoxide reductase subunit C, a key enzyme of the mycobacterial antioxidant defense system as well as its interaction with its reducing partner, Thioredoxin C

• Main Author: Wong, Chui Fann
• Other Authors: Gerhard Gruber
• Format: Theses and Dissertations
• Language: English
• Published: 2018
• Subjects: DRNTU::Science::Biological sciences
• Online Access: http://hdl.handle.net/10356/73476
• Institution: Nanyang Technological University

In 2015, the World Health Organization estimated that Tuberculosis (TB) infection affects a third of the world's population and is the leading cause of mortality caused by a single infectious agent. Through the years, effective drugs were designed to target its causative agent, Mycobacterium tu...