Enzymatic and structural insights into the mycobacterial alkylhydroperoxide reductase subunit C and repurposing of an antimalaria compound inhibiting the mycobacterial cytochrome BCC oxidase for tuberculosis disease

Tuberculosis (TB) is one of the leading contagious diseases that results in mortality. Treatment with antibiotics has been applied for TB however, with new forms of antibiotic resistance emerging, difficulty in treatment of TB was detected. In this study, alkylhydroperoxide reductase subunit C (MtAh...

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Bibliographic Details
Main Author: Chong, Sherilyn Shi Min
Other Authors: Gerhard Gruber
Format: Thesis-Doctor of Philosophy
Language:English
Published: Nanyang Technological University 2020
Subjects:
Online Access:https://hdl.handle.net/10356/143914
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Institution: Nanyang Technological University
Language: English