Characterization of the splicing function of pseudouridine Ψ5 in U1 small nuclear RNA

Pseudouridine (Ψ) is the major post-transcriptionally modified nucleotide in RNA. The 5’ end of U1 snRNA contains two evolutionarily conserved pseudouridines, Ψ5 and Ψ6, yet, their role in recognition of thousands of 5’ss variants remains to be established. Therefore, in our study, we investigated t...

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Bibliographic Details
Main Author: Yong, Jing Yen
Other Authors: Francesc Xavier Roca Castella
Format: Final Year Project
Language:English
Published: 2018
Subjects:
Online Access:http://hdl.handle.net/10356/74455
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Institution: Nanyang Technological University
Language: English