Development of 3D tethered particle motion as a tool to study conformational changes of biomolecules
Tethered particle motion is a simple yet powerful technique that allows researchers to study various protein-DNA interactions. By non-specifically anchoring a DNA onto the glass coverslip and attaching a fluorescent bead to the other end of the DNA through a biotin-avidin interaction, scientist have...
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Format: | Final Year Project |
Language: | English |
Published: |
2018
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Online Access: | http://hdl.handle.net/10356/75415 |
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Institution: | Nanyang Technological University |
Language: | English |