Development of 3D tethered particle motion as a tool to study conformational changes of biomolecules

Tethered particle motion is a simple yet powerful technique that allows researchers to study various protein-DNA interactions. By non-specifically anchoring a DNA onto the glass coverslip and attaching a fluorescent bead to the other end of the DNA through a biotin-avidin interaction, scientist have...

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Bibliographic Details
Main Author: Chan, Nicholas Zhen Woon
Other Authors: Phan Anh Tuan
Format: Final Year Project
Language:English
Published: 2018
Subjects:
Online Access:http://hdl.handle.net/10356/75415
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Institution: Nanyang Technological University
Language: English
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