Modelling Mitchell-Riley Syndrome in vitro using iPS cells derived from RFX6 mutant patient
The forkhead transcription factor Regulatory Factor X, 6 (RFX6) is essential for the development of the mammalian pancreas. In humans, RFX6 mutations are responsible for Mitchell-Riley Syndrome (MRS), which is characterized by neonatal diabetes with pancreatic hypoplasia. Similarly, Rfx6 mutant mice...
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| Format: | Theses and Dissertations |
| Language: | English |
| Published: |
2018
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| Online Access: | http://hdl.handle.net/10356/75844 |
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| Institution: | Nanyang Technological University |
| Language: | English |