Optimizing the synthesis of teixobactin and investigating the effects of cationicity of the macrocyclic pharmocophore on antibacterial activity

Following the widespread use and abuse of antibiotics, bacteria have evolved a diverse array of strategies to evade elimination by these antimicrobial drugs, a phenomenon commonly known as antibiotic resistance. The capacity for bacteria to develop resistance against multiple types of antibiotics p...

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Bibliographic Details
Main Author: Ng, Belle Min Yee
Other Authors: Liu Chuan Fa
Format: Final Year Project
Language:English
Published: 2019
Subjects:
Online Access:http://hdl.handle.net/10356/77124
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Institution: Nanyang Technological University
Language: English