Correlative light and electron microscopy analysis of telomere ultrastructure in immortalised mouse embryonic fibroblasts
Telomeres, the ends of eukaryotic chromosomes, consist of TTAGGG repeats, with DNA region, as well as a complex of six proteins known as the shelterin complex. One of the components of the complex, telomeric repeat-binding factor 2 (TRF2), binds the double-stranded region of telomere and is shown to...
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Format: | Final Year Project |
Language: | English |
Published: |
2019
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Online Access: | http://hdl.handle.net/10356/77824 |
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Institution: | Nanyang Technological University |
Language: | English |