Correlative light and electron microscopy analysis of telomere ultrastructure in immortalised mouse embryonic fibroblasts

Telomeres, the ends of eukaryotic chromosomes, consist of TTAGGG repeats, with DNA region, as well as a complex of six proteins known as the shelterin complex. One of the components of the complex, telomeric repeat-binding factor 2 (TRF2), binds the double-stranded region of telomere and is shown to...

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Bibliographic Details
Main Author: Agatha, Olivia
Other Authors: Sara Sandin
Format: Final Year Project
Language:English
Published: 2019
Subjects:
Online Access:http://hdl.handle.net/10356/77824
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Institution: Nanyang Technological University
Language: English