Correlative light and electron microscopy analysis of telomere ultrastructure in immortalised mouse embryonic fibroblasts

• المؤلف الرئيسي: Agatha, Olivia
• مؤلفون آخرون: Sara Sandin
• التنسيق: Final Year Project
• اللغة: English
• منشور في: 2019
• الموضوعات: DRNTU::Science::Biological sciences
• الوصول للمادة أونلاين: http://hdl.handle.net/10356/77824
• المؤسسة: Nanyang Technological University

Telomeres, the ends of eukaryotic chromosomes, consist of TTAGGG repeats, with DNA region, as well as a complex of six proteins known as the shelterin complex. One of the components of the complex, telomeric repeat-binding factor 2 (TRF2), binds the double-stranded region of telomere and is shown to...