An internal ribosome entry site (IRES) mutant library for tuning expression level of multiple genes in mammalian cells

An internal ribosome entry site (IRES) mutant library for tuning expression level of multiple genes in mammalian cells

A set of mutated Encephalomyocarditis virus (EMCV) internal ribosome entry site (IRES) elements with varying strengths is generated by mutating the translation initiation codons of 10th, 11th, and 12th AUG to non-AUG triplets. They are able to control the relative expression of multiple genes over a...

Full description

Saved in:
Bibliographic Details
Main Authors: Koh, Esther Y. C., Ho, Steven C. L., Mariati, Song, Zhiwei, Bi, Xuezhi, Bardor, Muriel, Yang, Yuansheng
Other Authors: Hendershot, Linda M.
Format: Article
Language:English
Published: 2015
Online Access:https://hdl.handle.net/10356/79242
http://hdl.handle.net/10220/38558
Tags: Add Tag
No Tags, Be the first to tag this record!
Institution: Nanyang Technological University
Language: English

Internet

https://hdl.handle.net/10356/79242
http://hdl.handle.net/10220/38558

Similar Items