Comprehensive splice-site analysis using comparative genomics

• Main Authors: Sheth, Nihar, Roca, Xavier, Roeder, Ted, Sachidanandam, Ravi, Hastings, Michelle L., Krainer, Adrian R.
• Other Authors: School of Biological Sciences
• Format: Article
• Language: English
• Published: 2012
• Subjects: DRNTU::Science::Biological sciences
• Online Access: https://hdl.handle.net/10356/79796; http://hdl.handle.net/10220/8868
• Institution: Nanyang Technological University

We have collected over half a million splice sites from five species—Homo sapiens, Mus musculus, Drosophila melanogaster, Caenorhabditis elegans and Arabidopsis thaliana—and classified them into four subtypes: U2-type GT–AG and GC–AG and U12-type GT–AG and AT–AC. We have also found new examples of r...