Quantitative model of R-loop forming structures reveals a novel level of RNA–DNA interactome complexity
R-loop is the structure co-transcriptionally formed between nascent RNA transcript and DNA template, leaving the non-transcribed DNA strand unpaired. This structure can be involved in the hyper-mutation and dsDNA breaks in mammalian immunoglobulin (Ig) genes, oncogenes and neurodegenerative disease...
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| Main Authors: | , , , |
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| Other Authors: | |
| Format: | Article |
| Language: | English |
| Published: |
2013
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| Subjects: | |
| Online Access: | https://hdl.handle.net/10356/79920 http://hdl.handle.net/10220/10922 |
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| Institution: | Nanyang Technological University |
| Language: | English |