Sustained delivery of siRNA/mesoporous silica nanoparticle complexes from nanofiber scaffolds for long-term gene silencing

A low toxicity and efficient delivery system is needed to deliver small interfering RNAs (siRNA) in vitro and in vivo. The use of mesoporous silica nanoparticles (MSN) is becoming increasingly common due to its biocompatibility, tunable pore size and customizable properties. However, bolus delivery...

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Bibliographic Details
Main Authors: Pinese, Coline, Lin, Junquan, Milbreta, Ulla, Li, Mingqiang, Wang, Yucai, Leong, Kam W., Chew, Sing Yian
Other Authors: School of Chemical and Biomedical Engineering
Format: Article
Language:English
Published: 2018
Subjects:
Online Access:https://hdl.handle.net/10356/80400
http://hdl.handle.net/10220/46518
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Institution: Nanyang Technological University
Language: English
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