Sustained delivery of siRNA/mesoporous silica nanoparticle complexes from nanofiber scaffolds for long-term gene silencing
A low toxicity and efficient delivery system is needed to deliver small interfering RNAs (siRNA) in vitro and in vivo. The use of mesoporous silica nanoparticles (MSN) is becoming increasingly common due to its biocompatibility, tunable pore size and customizable properties. However, bolus delivery...
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Main Authors: | Pinese, Coline, Lin, Junquan, Milbreta, Ulla, Li, Mingqiang, Wang, Yucai, Leong, Kam W., Chew, Sing Yian |
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Other Authors: | School of Chemical and Biomedical Engineering |
Format: | Article |
Language: | English |
Published: |
2018
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Subjects: | |
Online Access: | https://hdl.handle.net/10356/80400 http://hdl.handle.net/10220/46518 |
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Institution: | Nanyang Technological University |
Language: | English |
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