Monocyte cell membrane-derived nanoghosts for targeted cancer therapy

• Main Authors: Krishnamurthy, Sangeetha, Gnanasammandhan, M. K., Xie, Chen, Huang, K., Cui, M. Y., Chan, J. M.
• Other Authors: School of Chemical and Biomedical Engineering
• Format: Article
• Language: English
• Published: 2016
• Subjects: Serum stability; Mono-disperse
• Online Access: https://hdl.handle.net/10356/80507; http://hdl.handle.net/10220/40528
• Institution: Nanyang Technological University

Core-shell type ‘nanoghosts’ were synthesized with a drug-loaded biodegradable PLGA core and a monocyte cell membrane-derived shell. The nanoghosts were monodisperse with an average size <200 nm, and showed good serum stability for 120 h dox0rubicin loaded nanoghosts showed greater cellular uptak...