Monocyte cell membrane-derived nanoghosts for targeted cancer therapy
Core-shell type ‘nanoghosts’ were synthesized with a drug-loaded biodegradable PLGA core and a monocyte cell membrane-derived shell. The nanoghosts were monodisperse with an average size <200 nm, and showed good serum stability for 120 h dox0rubicin loaded nanoghosts showed greater cellular uptak...
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sg-ntu-dr.10356-805072023-12-29T06:49:03Z Monocyte cell membrane-derived nanoghosts for targeted cancer therapy Krishnamurthy, Sangeetha Gnanasammandhan, M. K. Xie, Chen Huang, K. Cui, M. Y. Chan, J. M. School of Chemical and Biomedical Engineering Serum stability Mono-disperse Core-shell type ‘nanoghosts’ were synthesized with a drug-loaded biodegradable PLGA core and a monocyte cell membrane-derived shell. The nanoghosts were monodisperse with an average size <200 nm, and showed good serum stability for 120 h dox0rubicin loaded nanoghosts showed greater cellular uptake and cytotoxicity compared to non-coated nanoparticle controls in metastatic MCF-7 breast cancer cell lines. Published version 2016-05-12T02:43:24Z 2019-12-06T13:51:05Z 2016-05-12T02:43:24Z 2019-12-06T13:51:05Z 2016 Journal Article Krishnamurthy, S., Gnanasammandhan, M. K., Xie, C., Huang, K., Cui, M. Y., & Chan, J. M. (2016). Monocyte cell membrane-derived nanoghosts for targeted cancer therapy. Nanoscale, 8(13), 6981-6985. doxo 2040-3372 https://hdl.handle.net/10356/80507 http://hdl.handle.net/10220/40528 10.1039/C5NR07588B en Nanoscale © 2016 The Royal Society of Chemistry. This article is licensed under a Creative Commons Attribution-NonCommercial 3.0 Unported Licence. 5 p. application/pdf |
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Nanyang Technological University |
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Serum stability Mono-disperse |
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Serum stability Mono-disperse Krishnamurthy, Sangeetha Gnanasammandhan, M. K. Xie, Chen Huang, K. Cui, M. Y. Chan, J. M. Monocyte cell membrane-derived nanoghosts for targeted cancer therapy |
| description |
Core-shell type ‘nanoghosts’ were synthesized with a drug-loaded biodegradable PLGA core and a monocyte cell membrane-derived shell. The nanoghosts were monodisperse with an average size <200 nm, and showed good serum stability for 120 h dox0rubicin loaded nanoghosts showed greater cellular uptake and cytotoxicity compared to non-coated nanoparticle controls in metastatic MCF-7 breast cancer cell lines. |
| author2 |
School of Chemical and Biomedical Engineering |
| author_facet |
School of Chemical and Biomedical Engineering Krishnamurthy, Sangeetha Gnanasammandhan, M. K. Xie, Chen Huang, K. Cui, M. Y. Chan, J. M. |
| format |
Article |
| author |
Krishnamurthy, Sangeetha Gnanasammandhan, M. K. Xie, Chen Huang, K. Cui, M. Y. Chan, J. M. |
| author_sort |
Krishnamurthy, Sangeetha |
| title |
Monocyte cell membrane-derived nanoghosts for targeted cancer therapy |
| title_short |
Monocyte cell membrane-derived nanoghosts for targeted cancer therapy |
| title_full |
Monocyte cell membrane-derived nanoghosts for targeted cancer therapy |
| title_fullStr |
Monocyte cell membrane-derived nanoghosts for targeted cancer therapy |
| title_full_unstemmed |
Monocyte cell membrane-derived nanoghosts for targeted cancer therapy |
| title_sort |
monocyte cell membrane-derived nanoghosts for targeted cancer therapy |
| publishDate |
2016 |
| url |
https://hdl.handle.net/10356/80507 http://hdl.handle.net/10220/40528 |
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1787136629826125824 |