Identification of a novel sequence type of Escherichia coli as the causative agent of pyelonephritis and bloodstream infection

Identification of a novel sequence type of Escherichia coli as the causative agent of pyelonephritis and bloodstream infection

Introduction: Globally, extra-intestinal pathogenic Escherichia coli are one of the predominant causative agents of bacteraemia. Case presentation: This case report outlines a presentation of community-acquired pyelonephritis and secondary bloodstream infection in an 81-year-old man. Laboratory inv...

Full description

Saved in:
Bibliographic Details
Main Authors: Mac Aogáin, Micheál, Miajlovic, Helen, Moloney, Geraldine, Chotirmall, Sanjay Haresh, Rogers, Thomas R., Smith, Stephen G. J.
Other Authors: Lee Kong Chian School of Medicine (LKCMedicine)
Format: Article
Language:English
Published: 2017
Subjects:
Escherichia coli ST-458
Bacteraemia
Online Access:https://hdl.handle.net/10356/80781
http://hdl.handle.net/10220/42230
Tags: Add Tag
No Tags, Be the first to tag this record!
Institution: Nanyang Technological University
Language: English
Description
Summary:Introduction: Globally, extra-intestinal pathogenic Escherichia coli are one of the predominant causative agents of bacteraemia. Case presentation: This case report outlines a presentation of community-acquired pyelonephritis and secondary bloodstream infection in an 81-year-old man. Laboratory investigations revealed that the causative isolate was a multi-drug-resistant E. coli of a novel multi-locus sequence type. This sequence type (ST) was designated ST-458 and was most closely related to the globally prevalent ST-131 lineage. Conclusion: This is the first report of a novel E. coli ST, ST-458, which caused pyelonephritis and bacteraemia.

Similar Items