Lamellar sheet exfoliation of single lipid vesicles by a membrane-active peptide

• Main Authors: Tabaei, Seyed Ruhollah, Cho, Nam-Joon
• Other Authors: School of Materials Science & Engineering
• Format: Article
• Language: English
• Published: 2016
• Subjects: Nanostructures
• Online Access: https://hdl.handle.net/10356/80927; http://hdl.handle.net/10220/40633
• Institution: Nanyang Technological University

Using total internal fluorescence microscopy, highly parallel measurements of single lipid vesicles unexpectedly reveal that a small fraction of vesicles rupture in multiple discrete steps when destabilized by a membrane-active peptide which is in contrast to classical solubilization models. To acco...