Delineation of Natural Killer Cell Differentiation from Myeloid Progenitors in Human

• Main Authors: Chen, Qingfeng, Ye, Weijian, Liu, Min, Tan, Shu Qi, Loh, Eva, Chang, Kenneth T. E., Tan, Thiam Chye, Preiser, Peter R., Tan, Wei Jian, Yong, Kylie Su Mei, Chen, Jianzhu
• Other Authors: School of Biological Sciences
• Format: Article
• Language: English
• Published: 2015
• Online Access: https://hdl.handle.net/10356/81095; http://hdl.handle.net/10220/39052
• Institution: Nanyang Technological University

Understanding of natural killer (NK) cell development in human is incomplete partly because of limited access to appropriate human tissues. We have developed a cytokine-enhanced humanized mouse model with greatly improved reconstitution and function of human NK cells. Here we report the presence of...