Dynamic Transcription of Distinct Classes of Endogenous Retroviral Elements Marks Specific Populations of Early Human Embryonic Cells

About half of the human genome consists of highly repetitive elements, most of which are considered dispensable for human life. Here, we report that repetitive elements originating from endogenous retroviruses (ERVs) are systematically transcribed during human early embryogenesis in a stage-specific...

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Bibliographic Details
Main Authors: Göke, Jonathan, Lu, Xinyi, Chan, Yun-Shen, Ng, Huck-Hui, Ly, Lam-Ha, Sachs, Friedrich, Szczerbinska, Iwona
Other Authors: School of Biological Sciences
Format: Article
Language:English
Published: 2016
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Online Access:https://hdl.handle.net/10356/82005
http://hdl.handle.net/10220/41057
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Institution: Nanyang Technological University
Language: English