A PRC2-dependent repressive role of PRDM14 in human embryonic stem cells and induced pluripotent stem cell reprogramming

by Su, I-hsin, Chan, Yun-Shen, Göke, Jonathan, Lu, Xinyi, Venkatesan, Nandini, Feng, Bo, Ng, Huck-Hui
Published 2013

Dynamic Transcription of Distinct Classes of Endogenous Retroviral Elements Marks Specific Populations of Early Human Embryonic Cells

by Göke, Jonathan, Lu, Xinyi, Chan, Yun-Shen, Ng, Huck-Hui, Ly, Lam-Ha, Sachs, Friedrich, Szczerbinska, Iwona
Published 2016

The retrovirus HERVH is a long noncoding RNA required for human embryonic stem cell identity

by Lu, Xinyi, Sachs, Friedrich, Ramsay, LeeAnn, Jacques, Pierre-Étienne, Göke, Jonathan, Bourque, Guillaume, Ng, Huck-Hui
Published 2016

Molecular features underlying neurodegeneration identified through in vitro modeling of genetically diverse parkinson’s disease patients

by Lin, Lin, Göke, Jonathan, Cukuroglu, Engin, Dranias, Mark R., VanDongen, Antonius M.J., Stanton, Lawrence W.
Published 2018

SON connects the splicing-regulatory network with pluripotency in human embryonic stem cells

by Lu, Xinyi, Göke, Jonathan, Sachs, Friedrich, Jacques, Pierre-Étienne, Liang, Hongqing, Feng, Bo, Bourque, Guillaume, Bubulya, Paula A., Ng, Huck-Hui
Published 2016

EZH2 promotes neoplastic transformation through VAV interaction-dependent extranuclear mechanisms

by Venkatesan, Nandini, Wong, Jong Fu, Tan, Kuan Pern, Chung, Hwa Hwa, Yau, Yin Hoe, Cukuroglu, Engin, Allahverdi, Abdollah, Nordenskiold, Lars, Goke, Jonathan, Geifman-Shochat, Susana, Lin, Valerie Chun Ling, Madhusudhan, M. S., Su, I-hsin
Published 2018

Long-read transcriptome sequencing reveals abundant promoter diversity in distinct molecular subtypes of gastric cancer

by Huang, Kie Kyon, Huang, Jiawen, Wu, Jeanie Kar Leng, Lee, Minghui, Tay, Su Ting, Kumar, Vikrant, Ramnarayanan, Kalpana, Padmanabhan, Nisha, Xu, Chang, Tan, Angie Lay Keng, Chan, Charlene, Kappei, Dennis, Göke, Jonathan, Tan, Patrick
Published 2022

A chemically defined feeder-free system for the establishment and maintenance of the human naive pluripotent state

by Szczerbinska, Iwona, Gonzales, Kevin Andrew Uy, Cukuroglu, Engin, Muhammad Nadzim Bin Ramli, Lee, Bertha Pei Ge, Tan, Cheng Peow, Wong, Cheng Kit, Rancati, Giulia Irene, Liang, Hongqing, Göke, Jonathan, Ng, Huck-Hui, Chan, Yun-Shen
Published 2020

Identification of differential RNA modifications from nanopore direct RNA sequencing with xPore

by Pratanwanich, Ploy N, Yao, Fei, Chen, Ying, Koh, Casslynn WQ, Wan, Yuk Kei, Hendra, Christopher, Poon, Polly, Goh, Yeek Teck, Yap, Phoebe ML, Chooi, Jing Yuan, Chng, Wee Joo, Ng, Sarah B, Thiery, Alexandre, Goh, WS Sho, Goke, Jonathan
Published 2021

Klf2 Is an Essential Factor that Sustains Ground State Pluripotency

by Yeo, Jia-Chi, Jiang, Jianming, Tan, Zi-Ying, Yim, Guo-Rong, Ng, Jia-Hui, Göke, Jonathan, Kraus, Petra, Liang, Hongqing, Gonzales, Kevin Andrew Uy, Chong, Han-Chung, Tan, Cheng-Peow, Lim, Yee-Siang, Tan, Nguan-Soon, Lufkin, Thomas, Ng, Huck-Hui
Published 2016

Epigenetic promoter alterations in GI tumour immune-editing and resistance to immune checkpoint inhibition

by Sundar, Raghav, Huang, Kie-Kyon, Kumar, Vikrant, Ramnarayanan, Kalpana, Demircioglu, Deniz, Her, Zhisheng, Ong, Xuewen, Isa, Zul Fazreen Bin Adam, Xing, Manjie, Tan, Angie Lay-Keng, Tai, David Wai Meng, Choo, Su Pin, Zhai, Weiwei, Lim, Jia Qi, Das Thakur, Meghna, Molinero, Luciana, Cha, Edward, Fasso, Marcella, Niger, Monica, Pietrantonio, Filippo, Lee, Jeeyun, Jeyasekharan, Anand D, Qamra, Aditi, Patnala, Radhika, Fabritius, Arne, De Simone, Mark, Yeong, Joe, Ng, Cedric Chuan Young, Rha, Sun Young, Narita, Yukiya, Muro, Kei, Guo, Yu Amanda, Skanderup, Anders Jacobsen, So, Jimmy Bok Yan, Yong, Wei Peng, Chen, Qingfeng, Goke, Jonathan, Tan, Patrick
Published 2022