The retrovirus HERVH is a long noncoding RNA required for human embryonic stem cell identity

The retrovirus HERVH is a long noncoding RNA required for human embryonic stem cell identity

Human endogenous retrovirus subfamily H (HERVH) is a class of transposable elements expressed preferentially in human embryonic stem cells (hESCs). Here, we report that the long terminal repeats of HERVH function as enhancers and that HERVH is a nuclear long noncoding RNA required to maintain hESC i...

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Bibliographic Details
Main Authors: Lu, Xinyi, Sachs, Friedrich, Ramsay, LeeAnn, Jacques, Pierre-Étienne, Göke, Jonathan, Bourque, Guillaume, Ng, Huck-Hui
Other Authors: School of Biological Sciences
Format: Article
Language:English
Published: 2016
Subjects:
Long non-coding RNAs
Pluripotent stem cells
Online Access:https://hdl.handle.net/10356/81803
http://hdl.handle.net/10220/40971
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Institution: Nanyang Technological University
Language: English

Internet

https://hdl.handle.net/10356/81803
http://hdl.handle.net/10220/40971

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