Dynamic Transcription of Distinct Classes of Endogenous Retroviral Elements Marks Specific Populations of Early Human Embryonic Cells

• المؤلفون الرئيسيون: Göke, Jonathan, Lu, Xinyi, Chan, Yun-Shen, Ng, Huck-Hui, Ly, Lam-Ha, Sachs, Friedrich, Szczerbinska, Iwona
• مؤلفون آخرون: School of Biological Sciences
• التنسيق: مقال
• اللغة: English
• منشور في: 2016
• الموضوعات: transposon; embryo
• الوصول للمادة أونلاين: https://hdl.handle.net/10356/82005; http://hdl.handle.net/10220/41057

About half of the human genome consists of highly repetitive elements, most of which are considered dispensable for human life. Here, we report that repetitive elements originating from endogenous retroviruses (ERVs) are systematically transcribed during human early embryogenesis in a stage-specific...