Revisiting Frank-Starling: regulatory light chain phosphorylation alters the rate of force redevelopment (k_tr) in a length-dependent fashion
Force and power in cardiac muscle have a known dependence on phosphorylation of the myosin-associated regulatory light chain (RLC). We explore the effect of RLC phosphorylation on the ability of cardiac preparations to redevelop force (ktr ) in maximally activating [Ca2+ ]. Activation was achieved b...
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Main Authors: | Toepfer, Christopher N., West, Timothy G., Ferenczi, Michael Alan |
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Other Authors: | Lee Kong Chian School of Medicine (LKCMedicine) |
Format: | Article |
Language: | English |
Published: |
2016
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Subjects: | |
Online Access: | https://hdl.handle.net/10356/82094 http://hdl.handle.net/10220/41034 |
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Institution: | Nanyang Technological University |
Language: | English |
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