Molecular nonlinear dynamics and protein thermal uncertainty quantification

• المؤلفون الرئيسيون: Xia, Kelin, Wei, Guo-Wei
• مؤلفون آخرون: School of Physical and Mathematical Sciences
• التنسيق: مقال
• اللغة: English
• منشور في: 2016
• الموضوعات: Proteins; Protein folding
• الوصول للمادة أونلاين: https://hdl.handle.net/10356/82121; http://hdl.handle.net/10220/41112

This work introduces molecular nonlinear dynamics (MND) as a new approach for describing protein folding and aggregation. By using a mode system, we show that the MND of disordered proteins is chaotic while that of folded proteins exhibits intrinsically low dimensional manifolds (ILDMs). The stabili...